iBiomagazine

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Topoisomerase I (TOP1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Topoisomerase I (TOP1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Topoisomerase I (TOP1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Topoisomerase I (TOP1) in Tissue homogenates, cell lysates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Topoisomerase I (TOP1) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: A sandwich ELISA kit for detection of Topoisomerase I from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Topoisomerase I (TOP1) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Topoisomerase I (TOP1) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Topoisomerase I (TOP1) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Topoisomerase I (TOP1) in tissue homogenates, cell lysates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Topoisomerase I (TOP1) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Topoisomerase I (TOP1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Topoisomerase I (TOP1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Topoisomerase I (TOP1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Topoisomerase I (TOP1) in Tissue homogenates, cell lysates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Topoisomerase I (TOP1) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: Recombinant Human Topoisomerase I expressed in: E.coli

Description: A sandwich ELISA kit for detection of Topoisomerase I from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: A sandwich ELISA kit for detection of Topoisomerase I from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: A Rabbit polyclonal antibody against Human Topoisomerase I (TOP1)

Description: Bovine DNA Topoisomerase-I purified from bovine tissues by proprietary chromatographic techniques.

Description: This product includes 42 ul of 4 uM E. coli topoisomerase I

Description: Rabbit Monoclonal TOP1/Topoisomerase I Antibody. Validated in IF, WB and tested in Human, Mouse.

Description: A Rabbit polyclonal antibody against Human Topoisomerase I (TOP1). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Human Topoisomerase I (TOP1). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Human Topoisomerase I (TOP1). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Human Topoisomerase I (TOP1). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Human Topoisomerase I (TOP1). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Human Topoisomerase I (TOP1). This antibody is labeled with PE.

Description: A Rabbit polyclonal antibody against Human Topoisomerase I (TOP1). This antibody is labeled with APC-Cy7.

Description: Recombinant TOP1 70kDa protein is an enzyme fragment having a molecular mass of 69,199 Dalton (pH 9.4). TOP1 70kDa protein is fused to a hexa-histidine purification tag.

Description: Quantitative sandwich ELISA for measuring Rat DNA topoisomerase 1 (TOP1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Rat DNA topoisomerase 1 (TOP1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Rat DNA topoisomerase 1 (TOP1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

Description: Quantitative sandwich ELISA for measuring Mouse DNA topoisomerase 1 (TOP1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Mouse DNA topoisomerase 1 (TOP1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Mouse DNA topoisomerase 1 (TOP1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human DNA topoisomerase 1 (TOP1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human DNA topoisomerase 1 (TOP1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human DNA topoisomerase 1 (TOP1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Recombinant Vaccinia virus DNA topoisomerase 1B(TOP1) expressed in E.coli

Description: DNA Topoisomerase-I Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 91,576 Dalton (excluding glycosilation) 102 kDa total mass. The TOP1 is expressed with a -6xHis tag and purified by proprietary chromatographic techniques.

Description: Mouse polyclonal to Topoisomerase I

Description: Description of target: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. Involved in the circadian transcription of the core circadian clock component ARNTL/BMAL1 by altering the chromatin structure around the ROR response elements (ROREs) on the ARNTL/BMAL1 promoter.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.078 ng/mL

Description: Description of target: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. Involved in the circadian transcription of the core circadian clock component ARNTL/BMAL1 by altering the chromatin structure around the ROR response elements (ROREs) on the ARNTL/BMAL1 promoter.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.056 ng/mL

Description: The substance Camptothecin is a topoisomerase i inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble to 5 mM in DMSO.

Description: The substance Camptothecin is a topoisomerase i inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble to 5 mM in DMSO.

Description: Mouse monoclonal to Topoisomerase I

Description: Mouse monoclonal to Topoisomerase I

Description: A Rabbit polyclonal antibody against Rat Topoisomerase I, Mitochondrial (TOP1MT)

Description: The substance Irinotecan HCl is a topoisomerase i inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble to 50 mg/ml in DMSO.

Description: The substance Irinotecan HCl is a topoisomerase i inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble to 50 mg/ml in DMSO.

Description: Recombinant Mouse Topoisomerase I, Mitochondrial expressed in: E.coli

Description: Recombinant Rat Topoisomerase I, Mitochondrial expressed in: E.coli

Description: This product includes 20 ul of 500 U/ul of purified human Topoisomerase I form sf9 cells and 1 ml of 10 x assay buffer.

Description: This product includes 50 ul of 2,000 U/ul of purified human Topoisomerase I form sf9 cells and 10 ml of 10 x assay buffer

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Description: A Rabbit polyclonal antibody against Rat Topoisomerase I, Mitochondrial (TOP1MT). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Rat Topoisomerase I, Mitochondrial (TOP1MT). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Rat Topoisomerase I, Mitochondrial (TOP1MT). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Rat Topoisomerase I, Mitochondrial (TOP1MT). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Rat Topoisomerase I, Mitochondrial (TOP1MT). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Rat Topoisomerase I, Mitochondrial (TOP1MT). This antibody is labeled with PE.

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF405S conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF405S conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF405M conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF405M conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), Biotin conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), Biotin conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), PerCP conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), RPE conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF594 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF594 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), APC conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF680R conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF680R conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), Concentration: 0.2mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), Concentration: 0.2mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF488A conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF488A conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF568 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF568 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF647 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF647 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF640R conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF640R conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF543 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF543 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF660R conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF660R conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF680 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF680 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF555 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF555 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF770 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), CF770 conjugate, Concentration: 0.1mg/mL

Description: Primary antibody against Topoisomerase I, MT(TOP1MT/488), 1mg/mL

Description: Recombinant protein for human DNA topoisomerase I, mitochondrial

Description: Description of target: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.059 ng/mL

Description: Description of target: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. Involved in the circadian transcription of the core circadian clock component ARNTL/BMAL1 by altering the chromatin structure around the ROR response elements (ROREs) on the ARNTL/BMAL1 promoter.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.078 ng/mL

Description: Description of target: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.057ng/mL

Description: Description of target: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. Involved in the circadian transcription of the core circadian clock component ARNTL/BMAL1 by altering the chromatin structure around the ROR response elements (ROREs) on the ARNTL/BMAL1 promoter.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 0.059ng/mL

Description: This product includes the reaction buffer (T1 Buffer), supercoiled plasmid DNA and fluorescence dye H19 for assaying 20 DNA relaxation reactions in a 96-well plate assay format or 40 assays in a 384-well assay format. The reaction buffer is optimized for bacterial topoisomerase I.

Description: This product includes 480 ul of 10 x Buffer HT1, 405 ul of 10 x supercoiled plasmid DNA, 20 ul of 1500 x Dye H19 and 3000 ul of 10 x H19 dilution buffer. It is for 100 DNA relaxation assays in a 96-well plate format or 200 assays in a 384-well assay format. Human topo I enzyme in not included and can be purchased separately.

Description: A sandwich quantitative ELISA assay kit for detection of Rat Topoisomerase II (TOP2) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Rat Topoisomerase II (TOP2) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Topoisomerase II (TOP2) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Topoisomerase II (TOP2) in Tissue homogenates, cell lysates and other biological fluids.