iBiomagazine

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 7 (SIRT7) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 7 (SIRT7) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 7 (SIRT7) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 7 (SIRT7) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Sirtuin 7 (SIRT7) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: A sandwich ELISA kit for detection of Sirtuin 7 from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Sirtuin 7 (SIRT7) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Sirtuin 7 (SIRT7) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Sirtuin 7 (SIRT7) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Sirtuin 7 (SIRT7) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Sirtuin 7 (SIRT7) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: Recombinant Human Sirtuin 7 expressed in: E.coli

Description: Recombinant Rat Sirtuin 7 expressed in: E.coli

Description: Recombinant Rat Sirtuin 7 expressed in: E.coli

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7)

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7)

Description: A sandwich ELISA kit for detection of Sirtuin 7 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SIRT7 / Sirtuin 7 . This antibody is tested and proven to work in the following applications:

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with PE.

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with PE.

Description: A Rabbit polyclonal antibody against Human Sirtuin 7 (SIRT7)

Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with APC-Cy7.

Description: A Rabbit polyclonal antibody against Rat Sirtuin 7 (SIRT7). This antibody is labeled with APC-Cy7.

Description: A Rabbit polyclonal antibody against Human Sirtuin 7 (SIRT7). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Human Sirtuin 7 (SIRT7). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Human Sirtuin 7 (SIRT7). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Human Sirtuin 7 (SIRT7). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Human Sirtuin 7 (SIRT7). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Human Sirtuin 7 (SIRT7). This antibody is labeled with PE.

Description: Quantitative sandwich ELISA for measuring Human NAD-dependent deacetylase sirtuin 7 (SIRT7)  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human NAD-dependent deacetylase sirtuin 7 (SIRT7)  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human NAD-dependent deacetylase sirtuin 7 (SIRT7)  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: A Rabbit polyclonal antibody against Human Sirtuin 7 (SIRT7). This antibody is labeled with APC-Cy7.

Description: Description of target: NAD-dependent protein deacetylase that specifically mediates deacetylation of histone H3 at 'Lys-18' (H3K18Ac). In contrast to other histone deacetylases, displays selectivity for a single histone mark, H3K18Ac, directly linked to control of gene expression. H3K18Ac is mainly present around the transcription start site of genes and has been linked to activation of nuclear hormone receptors. SIRT7 thereby acts as a transcription repressor. Moreover, H3K18 hypoacetylation has been reported as a marker of malignancy in various cancers and seems to maintain the transformed phenotype of cancer cells. These data suggest that SIRT7 may play a key role in oncogenic transformation by suppresses expression of tumor suppressor genes by locus-specific deacetylation of H3K18Ac at promoter regions. Also required to restore the transcription of ribosomal RNA (rRNA) at the exit from mitosis: promotes the association of RNA polymerase I with the rDNA promoter region and coding region. Stimulates transcription activity of the RNA polymerase I complex. May also deacetylate p53/TP53 and promotes cell survival, however such data need additional confirmation. ;Species reactivity: Rat;Application: ELISA;Assay info: ;Sensitivity: < 0.061ng/mL

Description: Human Sirtuin 7 (GenBank Accession No. NM_016538), full length with C-terminal FLAG-tag, MW= 46 kDa, expressed in an E. coli expression system.

Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Angiotensin 1-7 (Ang1-7) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Angiotensin 1-7 (Ang1-7) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Description: A competitive ELISA for quantitative measurement of Rat SIRTUIN-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat SIRTUIN-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat SIRTUIN-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat SIRTUIN-6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat SIRTUIN-6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat SIRTUIN-6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat Sirtuin 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat Sirtuin 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat Sirtuin 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: Description of target: NAD-dependent protein deacetylase that specifically mediates deacetylation of histone H3 at 'Lys-18' (H3K18Ac). In contrast to other histone deacetylases, displays selectivity for a single histone mark, H3K18Ac, directly linked to control of gene expression. H3K18Ac is mainly present around the transcription start site of genes and has been linked to activation of nuclear hormone receptors. SIRT7 thereby acts as a transcription repressor. Moreover, H3K18 hypoacetylation has been reported as a marker of malignancy in various cancers and seems to maintain the transformed phenotype of cancer cells. These data suggest that SIRT7 may play a key role in oncogenic transformation by suppresses expression of tumor suppressor genes by locus-specific deacetylation of H3K18Ac at promoter regions. Required to restore the transcription of ribosomal RNA (rRNA) at the exit from mitosis. Promotes the association of RNA polymerase I with the rDNA promoter region and coding region. Stimulates transcription activity of the RNA polymerase I complex. May also deacetylate p53/TP53 and promotes cell survival, however such data need additional confirmation.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.087 ng/mL

Description: Description of target: ;Species reactivity: Bovine;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity:

Description: Description of target: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.1 ng/mL

Description: Description of target: SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.27ng/mL

Description: A sandwich quantitative ELISA assay kit for detection of Rat Sirtuin 1 (SIRT1) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Rat Sirtuin 1 (SIRT1) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Rat Sirtuin 3 (SIRT3) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Rat Sirtuin 3 (SIRT3) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 1 (SIRT1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 1 (SIRT1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 1 (SIRT1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 1 (SIRT1) in Tissue homogenates, cell lysates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Sirtuin 1 (SIRT1) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 3 (SIRT3) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 3 (SIRT3) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 3 (SIRT3) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 3 (SIRT3) in tissue homogenates, cell lysates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Sirtuin 3 (SIRT3) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 2 (SIRT2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.